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Leveraging Evolutionary Trade-Offs and Phage Selection Pressure to Reduce Bacterial Pathogenicity
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- 1 Intro
- 2 Leveraging evolutionary trade-offs and phage selection pressure to reduce bacterial pathogenicity
- 3 Phage therapy: a renewed approach
- 4 Isolating phage candidates
- 5 Incorporating genome sequencing
- 6 Measuring phage host-range
- 7 Characterizing phage binding
- 8 Trade-offs WOULD benefit phage therapy
- 9 Identify phages that drive antibiotic resistance trade-offs
- 10 Determine likelihood that mutations cause trade-offs
- 11 Identify phages that drive virulence trade-offs
- 12 Trade-ups WOULD NOT benefit phage therapy
- 13 Case 1: Emergency phage therapy in human volunteer
- 14 Examining clinical samples pre- vs. post-therapy
- 15 Evolutionary prediction
